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Nanopartz Microgold

Nanopartz™ has developed a brand new material - Microgold - the largest monodisperse gold particles available. Microgold are 75-100 nanometers in diameter and up to 1 micron in length. Microgold are the largest known "nanoparticles" available - and the largest that can still be considered nanoparticles. These particles match the wavelength of light in the longitudinal dimension providing single particle detection under white light microscopy with simple instrumentation. They have approximately 100 times the scattering cross section as a 100 nm spherical gold nanoparticle, 100,000 to 1,000,000 times the scattering of a 1.4 nm gold nanoparticle. As with all of Nanopartz products, they are highly monodisperse.

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Bare Microgold for Research
Bare Microgold for Research
Part# A13-(LENGTH)-(VOL); this product replaces the 70- series products.
Sterilization
Certified Sterilized (+$150.00)
Endotoxin
Endotoxin Purified and Certified (+$250.00)
Price: $150.00

 

Part #
Diameter (nm)
Length (nm)
Aspect Ratio
Peak SPR Wave (nm)
SPR OD (1cm)
Microgold Vol (nm3)
Microgold /mL
Wt. conc (ug/ml)
Wt. %
PPM
Molarity (pM)
SPR Molar Ext. (M-1cm-1)
A13-500
75
500
6.7
510
0.05
2.10E+06
1.24E+09
50
0.01%
50
2.06
2.43E+07
A13-1000
100
1000
10
510
0.05
7.59E+06
3.42E+08
50
0.01%
50
0.57
8.78E+07
 
CTAB
In batch size variation
< 10% CV
Shape monodispersity
>95% microgold
Surface charge (zeta)
40mV
pH
5
Residual Chemicals
5mM CTAB
CTAB
5mM
Added Diameter
Included
Bond
Adsorbed

 

CTABCTAB Structure

CTAB

Hexadecyltrimethylammonium bromide (CTAB) (C16H33)N(CH3)3Br, cetyltrimethylammonium bromide. As any surfactant, it forms micelles in aqueous solutions. At 303 K (30 °C) it forms micelles with aggregation number 75-120 (depending on method of determination, usually average ~95) and degree of ionization α (fractional charge) 0.2–0.1 (from low to high concentration). The standard constant of Br- counterion binding to the micelle at 303 K (30 °C) is K° ≈ 400.

 

Composition

These bare Microgold are shipped in  DI water in 5mM CTAB.

Custom Formulation

Diameters 75 and 100nm, lengths 500 and 1000nm.  Other sizes are special order.  Please contact us.

Quantity

This product is available in 5mL and larger. For orders larger than 100mL, or for orders amounting over 10L per annum, please contact sales for quantity pricing.

Delivery

Standard sizes are in stock. Special order sizes are shipped in two weeks or less. All domestic shipments are sent Fed Ex Standard Overnight delivery, international Fed Ex Priority 2 day. No shipments on Fridays.

Conjugations

This product comes standard with CTAB.

Shelf Life/Storage Temperature

This product is guaranteed for six months and should be stored at 4°C after opening. Care must be taken to only use sterile glassware when working with this product.

Toxicity

This product is known to be cytotoxic.

Certifications

This product is manufactured using our audited ISO 9000 quality control system. Every order comes with a Certificate of Analysis. We use NIST traceable:

UV-VIS (Agilent 8453) for extinction and concentration measurements

NIR (Cary 500) for NIR extinction and concentration measurements

DLS (Malvern Nano ZS) for zeta potential measurement

ICP-MS (Varian 820-MS) for gold mass measurements

TEM (Phillips CM-100 100KV) for sizing

The manufacturing method for these microparticles are based on our proprietary methods. This invention allows for the manufacturing of highly monodisperse gold microparticles. Micron sized particles are advantageous for white light microscopy applications as single particles can be seen under 40x objectives. This product replaces silver growth chemistries and its size is particularly advantageous in cellular uptake.

All of these "bare" particles are capped with ligands that are easily replaced with thiol and charge chemistries.

 

 

  • Largest know gold nanomaterial.
  • Single particles can be seen in white light microscopy.
  • Many conjugation options.
  • Advantageous size for intracellular uptake.
  • Perfect for microscopy labeling without silver growth.
  • Applications in tribological additives.
  • Large size enables use as labels in electron microscopy.

 

Can I use these bare microgold particles in my in-vitro experiments?

The CTAB provides a positive zeta potential that is very attractive for intercellular uptake. However, the CTAB is not covalently bound and is known to be cytotoxic. We recommend our MUTAB coated microgold that you can find in our in-vitro section.

What is the SPR for this product?

There is no Surface Plasmon Resonance for this particle as the diameter and length are too large, so these are not recommended for dark field microscopy. However, they are large enough to reflect light and are very advantageous for bright field microscopy.

Why are these particle so advantageous for in-vitro applications?

They have been shown to be the perfect size for intercellular uptake.

"I just wanted to say thank you! I am very proud of this research and I could not have done it without your nanoparticles and support. Look in the future for published work by us using these nanoparticles as well. Should be happening in the next few months. Thanks again."

Kellie Waterman 
Graduate Student 
Worcester Polytechnic University

 

Shape-dependent oriented trapping and scaffolding of plasmonic nanoparticles by topological defects for self-assembly of colloidal dimers in liquid crystals

B Senyuk, JS Evans, PJ Ackerman, T Lee, P Manna… - Nano …, 2012 - ACS Publications
... and surface chemistry (Table 1). Ethanol dispersions of microgolds (MGs), starfruits (SFs),
nanobursts (NBs) and nanorods (GNRs) with NSol(akyl acrylate) polymer conjugation (Figure
1a–d) were obtained from Nanopartz, Inc. ... Microgold (MG), NSol(akyl acrylate), 150, 800, 235, ...