Self Assembled Monolayer, Alkane Thiol Functionalized Gold Nanoparticles - Nanopartz

Nanopartz Self Assembled Monolayer, Alkane Thiol Functionalized Gold Nanoparticles includes the full line of Monodisperse Accurate Spherical Gold Nanoparticles, Gold Nanorods, Microgold, and Gold Nanowire product familes functionalized with Self Assembled Monolayers (SAMs), or otherwise know as alkanethiols or molecular surface modifiers (MSMs). We offer the most popular covalent alkyl, functional, protected, ring and other self assembly materials on gold nanoparticles - from 1 carbon cysteamine to 16 carbon Mercaptohexadecanoic acid, and many in between - in all types of solvents. Upon conjugation, not only is every batch is completely purified, it is characterized including size, monodispersity, aggregation, residual chemicals, and concentration. A Certificate of Analysis (COA) is provided for every order exhibiting TEM and UV-VIS images and data, as well as DLS data.

 

image_9

 

Part #
Diameter (nm)
Peak SPR Wavelength (nm)
NPS/ml
Molarity (pM)
Moles
Molar Ext. (M-1cm-1)
Absorption Molar Ext. (M-1cm-1)
Scattering Molar Ext. (M-1cm-1)
Size Dispersity %PDI
Size Accuracy (+/- nm)
B11-1.8
1.8
n/a
4.25E+16
7.10E+07
7.09E-08
7.05E+05
7.05E+05
0.00E+00
<35%
0.1
B11-2.2
2.2
n/a
2.33E+16
3.90E+07
3.88E-08
1.29E+06
1.29E+06
0.00E+00
<25%
0.1
B11-3
3
n/a
9.19E+15
1.50E+07
1.53E-08
3.26E+06
3.26E+06
0.00E+00
<20%
0.1
B11-4
4
n/a
3.88E+15
6.50E+06
6.46E-09
7.74E+06
7.74E+06
0.00E+00
<20%
1
B11-5
5
512
1.99E+15
3.30E+06
3.31E-09
1.51E+07
1.51E+07
0.00E+00
<20%
2
B11-10
10
516
2.48E+14
4.10E+05
4.14E-10
1.21E+08
1.21E+08
0.00E+00
<15%
2
B11-15
15
518
7.35E+13
1.20E+05
1.23E-10
4.08E+08
4.08E+08
0.00E+00
<15%
2
B11-20
20
520
3.10E+13
5.20E+04
5.17E-11
9.67E+08
9.67E+08
0.00E+00
<10%
2
B11-25
25
521
1.59E+13
2.60E+04
2.65E-11
1.89E+09
1.89E+09
0.00E+00
<10%
2
B11-30
30
523
9.19E+12
1.50E+04
1.53E-11
3.26E+09
3.26E+09
0.00E+00
<6%
2
B11-35
35
526
5.79E+12
9.60E+03
9.65E-12
5.18E+09
5.18E+09
0.00E+00
<6%
2
B11-40
40
527
3.88E+12
6.50E+03
6.46E-12
7.74E+09
7.72E+09
2.24E+07
<4%
2
B11-45
45
529
2.72E+12
4.50E+03
4.54E-12
1.10E+10
1.08E+10
2.03E+08
<4%
2
B11-50
50
531
1.99E+12
3.30E+03
3.31E-12
1.51E+10
1.45E+10
5.88E+08
<4%
2
B11-55
55
533
1.49E+12
2.50E+03
2.49E-12
2.01E+10
1.88E+10
1.30E+09
<4%
2
B11-60
60
536
1.15E+12
1.90E+03
1.91E-12
2.61E+10
2.36E+10
2.48E+09
<4%
2
B11-65
65
539
9.04E+11
1.50E+03
1.51E-12
3.32E+10
2.89E+10
4.33E+09
<4%
2
B11-70
70
542
7.23E+11
1.20E+03
1.21E-12
4.15E+10
3.44E+10
7.09E+09
<4%
2
B11-75
75
545
5.88E+11
9.80E+02
9.80E-13
5.10E+10
4.00E+10
1.10E+10
<4%
2
B11-80
80
549
4.85E+11
8.10E+02
8.08E-13
6.19E+10
4.54E+10
1.65E+10
<4%
2
B11-85
85
553
4.04E+11
6.70E+02
6.73E-13
7.42E+10
5.03E+10
2.39E+10
<4%
2
B11-90
90
558
3.40E+11
5.70E+02
5.67E-13
8.81E+10
5.44E+10
3.37E+10
<4%
2
B11-95
95
563
2.89E+11
4.80E+02
4.82E-13
1.04E+11
5.72E+10
4.65E+10
<4%
2
B11-100
100
569
2.48E+11
4.10E+02
4.14E-13
1.21E+11
5.82E+10
6.27E+10
<4%
2
B11-150
150
612
7.35E+10
1.20E+02
1.23E-13
4.08E+11
0.00E+00
4.08E+11
<4%
10
B11-200
200
n/a
3.10E+10
5.20E+01
5.17E-14
9.67E+11
0.00E+00
9.67E+11
<4%
10
B11-500
500
n/a
1.99E+09
3.30E+00
3.31E-15
1.51E+13
0.00E+00
1.51E+13
<4%
50
B11-1000
1000
n/a
2.48E+08
4.10E-01
4.14E-16
1.21E+14
0.00E+00
1.21E+14
<4%
100
B11-1500
1500
n/a
7.35E+07
1.20E-01
1.23E-16
4.08E+14
0.00E+00
4.08E+14
<4%
100

 

Optical Density >= 50, 5 for sizes >=500nm
Wt conc = 2.5mg in 0.25mL volume typical
Wt % = 1%
ppm = 10000
%PDI = Std Dev/Size
See Tech Note TN801 for definition of terms and method of analysis
All specs typical. May vary batch to batch. Exact values are measured for each batch
Shape monodispersity (% spheres) > 99.9%
Solution default is 18MEG DI water
Residual Chemicals < 0.1%

 

 

Part #
Diameter (nm)
Length (nm)
Peak SPR Wave (nm)
Aspect Ratio
OD SPR (AU)
Peak LSPR Wave (nm)
OD LSPR (AU)
Nanorods /mL
Wt. conc (ug/ml)
Wt. %
PPM
Molarity (nM)
Picomoles
SPR Molar Ext. (M-1cm-1)
LSPR Molar Ext. (M-1cm-1)

Peak SPR

(nm)

SPR Linewidth 80% (nm)
B12-5-808
5
21
808
4.2
50
510
10
2.39E+14
1750
0.18%
1750
398.72
3.99E+02
1.25E+08
2.51E+07
794-829
100
B12-5-780
5
19
780
3.8
50
510
10
2.67E+14
1750
0.18%
1750
444.72
4.45E+02
1.12E+08
2.25E+07
765-794
100
B12-5-700
5
15
700
3
50
510
10
3.47E+14
1750
0.18%
1750
578.14
5.78E+02
8.65E+07
1.73E+07
675-725
100
B12-10-2100
10
175
2100
17.5
50
510
10
6.73E+12
1750
0.18%
1750
11.21
1.12E+01
4.46E+09
8.92E+08
1900-2300
300
B12-10-1400
10
102
1400
10.2
50
510
10
1.17E+13
1750
0.18%
1750
19.47
1.95E+01
2.57E+09
5.14E+08
1300-1500
150
B12-10-1200
10
81
1200
8.1
50
510
10
1.48E+13
1750
0.18%
1750
24.67
2.47E+01
2.03E+09
4.05E+08
1132-1300
150
B12-10-1064
10
67
1064
6.7
50
510
10
1.81E+13
1750
0.18%
1750
30.13
3.01E+01
1.66E+09
3.32E+08
1022-1132
150
B12-10-980
10
59
980
5.9
50
510
10
2.09E+13
1750
0.18%
1750
34.91
3.49E+01
1.43E+09
2.86E+08
965-1022
150
B12-10-950
10
55
950
5.5
50
510
10
2.22E+13
1750
0.18%
1750
37
3.70E+01
1.35E+09
2.70E+08
925-965
150
B12-10-900
10
50
900
5
50
510
10
2.47E+13
1750
0.18%
1750
41.11
4.11E+01
1.22E+09
2.43E+08
875-925
150
B12-10-850
10
45
850
4.5
50
510
10
2.78E+13
1750
0.18%
1750
46.25
4.63E+01
1.08E+09
2.16E+08
829-875
100
B12-10-808
10
41
808
4.1
50
510
10
3.10E+13
1750
0.18%
1750
51.68
5.17E+01
9.68E+08
1.94E+08
794-829
75
B12-10-780
10
38
780
3.8
50
510
10
3.36E+13
1750
0.18%
1750
56.06
5.61E+01
8.92E+08
1.78E+08
765-794
65
B12-10-750
10
35
750
3.5
50
510
10
3.70E+13
1750
0.18%
1750
61.67
6.17E+01
8.11E+08
1.62E+08
725-765
50
B12-10-700
10
29
700
2.9
50
510
10
4.44E+13
1750
0.18%
1750
74
7.40E+01
6.76E+08
1.35E+08
675-725
40
B12-10-650
10
24
650
2.4
50
510
10
5.55E+13
1750
0.18%
1750
92.5
9.25E+01
5.41E+08
1.08E+08
625-675
40
B12-10-600
10
19
600
1.9
50
510
10
7.40E+13
1750
0.18%
1750
123.34
1.23E+02
4.05E+08
8.11E+07
575-625
40
B12-25-1400
25
245
1400
9.8
50
514
15
1.12E+12
2500
0.25%
2500
1.86
1.86E+00
2.69E+10
8.06E+09
1232-1500
150
B12-25-1064
25
137
1064
5.5
50
514
15
2.05E+12
2500
0.25%
2500
3.42
3.42E+00
1.46E+10
4.38E+09
1022-1232
150
B12-25-980
25
119
980
4.8
50
514
15
2.39E+12
2500
0.25%
2500
3.98
3.98E+00
1.26E+10
3.77E+09
965-1022
150
B12-25-950
25
102
950
4.1
50
514
15
2.82E+12
2500
0.25%
2500
4.7
4.70E+00
1.06E+10
3.19E+09
925-965
150
B12-25-900
25
96
900
3.8
50
514
15
3.01E+12
2500
0.25%
2500
5.02
5.02E+00
9.95E+09
2.99E+09
875-925
150
B12-25-850
25
93
850
3.7
50
514
15
3.12E+12
2500
0.25%
2500
5.2
5.20E+00
9.61E+09
2.88E+09
829-875
150
B12-25-808
25
90
808
3.6
50
514
15
3.24E+12
2500
0.25%
2500
5.39
5.39E+00
9.27E+09
2.78E+09
794-829
150
B12-25-780
25
87
780
3.5
50
514
15
3.36E+12
2500
0.25%
2500
5.6
5.60E+00
8.93E+09
2.68E+09
765-794
150
B12-25-750
25
85
750
3.4
50
514
15
3.45E+12
2500
0.25%
2500
5.75
5.75E+00
8.70E+09
2.61E+09
725-765
65
B12-25-700
25
75
700
3
50
514
15
3.96E+12
2500
0.25%
2500
6.61
6.61E+00
7.57E+09
2.27E+09
675-725
60
B12-25-650
25
71
650
2.8
50
514
15
4.22E+12
2500
0.25%
2500
7.03
7.03E+00
7.11E+09
2.13E+09
625-675
60
B12-25-600
25
57
600
2.3
50
514
15
5.43E+12
2500
0.25%
2500
9.05
9.05E+00
5.52E+09
1.66E+09
575-625
60
B12-25-550
25
34
550
1.4
50
514
15
1.01E+13
2500
0.25%
2500
16.91
1.69E+01
2.96E+09
8.87E+08
525-575
60
B12-40-1064
40
208
850
5.2
50
520
20
5.30E+11
2500
0.25%
2500
0.88
8.84E-01
5.66E+10
2.26E+10
1022-1232
150
B12-40-980
40
180
850
4.5
50
520
20
6.19E+11
2500
0.25%
2500
1.03
1.03E+00
4.84E+10
1.94E+10
875-1022
150
B12-40-850
40
148
850
3.7
50
520
20
7.67E+11
2500
0.25%
2500
1.28
1.28E+00
3.91E+10
1.57E+10
829-875
150
B12-40-808
40
134
808
3.4
50
520
20
8.56E+11
2500
0.25%
2500
1.43
1.43E+00
3.51E+10
1.40E+10
794-829
150
B12-40-780
40
124
780
3.1
50
520
20
9.33E+11
2500
0.25%
2500
1.55
1.55E+00
3.22E+10
1.29E+10
765-794
150
B12-40-750
40
112
750
2.8
50
520
20
1.05E+12
2500
0.25%
2500
1.74
1.74E+00
2.87E+10
1.15E+10
725-765
150
B12-40-700
40
92
700
2.3
50
520
20
1.31E+12
2500
0.25%
2500
2.19
2.19E+00
2.29E+10
9.14E+09
675-725
60
B12-40-650
40
80
650
2
50
520
20
1.55E+12
2500
0.25%
2500
2.58
2.58E+00
1.94E+10
7.75E+09
625-675
60
B12-40-600
40
68
600
1.7
50
520
20
1.89E+12
2500
0.25%
2500
3.15
3.15E+00
1.59E+10
6.35E+09
575-625
60
B12-40-550
40
60
550
1.5
50
520
20
2.21E+12
2500
0.25%
2500
3.69
3.69E+00
1.36E+10
5.42E+09
525-575
60
B12-50-1064
50
245
1064
4.9
50
530
25
2.89E+11
2500
0.25%
2500
0.48
4.82E-01
1.04E+11
5.18E+10
980-1232
150
B12-50-808
50
145
808
2.9
50
530
25
5.15E+11
2500
0.25%
2500
0.86
8.58E-01
5.83E+10
2.91E+10
750-850
150
B12-50-700
50
110
700
2.2
50
530
25
7.08E+11
2500
0.25%
2500
1.18
1.18E+00
4.24E+10
2.12E+10
650-750
150
B12-50-600
50
100
600
2
50
530
25
7.93E+11
2500
0.25%
2500
1.32
1.32E+00
3.78E+10
1.89E+10
550-650
150
B12-70-750
70
120
750
1.7
50
530
25
3.49E+11
2500
0.25%
2500
0.58
5.81E-01
8.60E+10
4.30E+10
700-800
150
B12-70-650
70
105
650
1.5
50
530
25
4.13E+11
2500
0.25%
2500
0.69
6.88E-01
7.27E+10
3.63E+10
600-700
150
B12-70-550
70
91
550
1.3
50
530
25
4.98E+11
2500
0.25%
2500
0.83
8.30E-01
6.02E+10
3.01E+10
500-600
150

 

Optical Density >= 200, volume = 0.25mL
All specs typical. May vary batch to batch. Exact values are measured for each batch
Solution default is 18MEG DI water
Residual Chemicals < 0.1%

 

 

 

Part #
Diameter (nm)
Length (nm)
Aspect Ratio
Peak SPR Wave (nm)
SPR OD (1cm)
Microgold /mL
moles
Wt. conc (ug/ml)
Wt. %
PPM
Molarity (pM)
SPR Molar Ext. (M-1cm-1)
B13-500
75
500
6.7
510
0.25
6.18E+09
1.03E-14
250
0.03%
250
10.3
2.43E+07
B13-1000
100
1000
10
510
0.25
1.71E+09
2.85E-15
250
0.03%
250
2.85
8.78E+07

 

SPR = Transverse SPR peak
Longitudinal has no SPR peak
Shape monodispersity (% rods) > 95%
Size variation +/-10% (both dimensions)

 

 

Part #
Diameter (nm)
Length (nm)
Aspect Ratio
Peak SPR Wave (nm)
Nanowires Vol (nm3)
Nanowires /mL
Wt. conc (ug/ml)
Wt. %
PPM
Molarity (pM)
SPR Molar Ext. (M-1cm-1)
B14-1000
75
1000
13
510
4.31E+06
3.01E+09
250
0.03%
250
5.02
9.96E+06
B14-2000
75
2000
27
510
8.72E+06
1.49E+09
250
0.03%
250
2.48
2.02E+07
B14-4000
75
4000
53
510
1.76E+07
7.39E+08
250
0.03%
250
1.23
4.06E+07
B14-6000
75
6000
80
510
2.64E+07
4.91E+08
250
0.03%
250
0.82
6.10E+07
B14-10000
75
10000
133
510
4.40E+07
2.94E+08
250
0.03%
250
0.49
1.02E+08
B14-20000
100
20000
200
510
1.57E+08
8.27E+07
250
0.03%
250
0.14
3.63E+08
B14-40000
140
40000
286
510
6.15E+08
2.11E+07
250
0.03%
250
0.04
1.42E+09

 

SPR = Transverse SPR peak
Longitudinal has no SPR peak
Shape monodispersity (% rods) > 95%
Size variation +/-10% (both dimensions)

 

Alkanethiol functionalized Gold Nanorod

 

Alkanethiol Functionalized Gold Nanorods

 

Molecular Surface Modifier Thiol Type Molecular Formula
1-Butanethiol Alkyl Thiols C4H10S
1-Decanethiol Alkyl Thiols C10H22S
1-Dodecanethiol Alkyl Thiols C12H26S
1-Heptanethiol Alkyl Thiols C7H16S
1-Hexadecanethiol Alkyl Thiols C16H34S
1-Hexanethiol  Alkyl Thiols C6H14S
1-Nonanethiol  Alkyl Thiols C9H20S
1-Octadecanethiol  Alkyl Thiols C18H38S
1-Octanethiol Alkyl Thiols C8H18S
1-Pentadecanethiol  Alkyl Thiols C15H32S
1-Pentanethiol Alkyl Thiols C5H12S
1-Propanethiol  Alkyl Thiols C3H8S
1-Tetradecanethiol  Alkyl Thiols C14H30S
1-Undecanethiol  Alkyl Thiols C11H24S
1H,1H,2H,2H-Perfluorodecanethiol  Alkyl Thiols C10H5F17S
2-Ethylhexanethiol  Alkyl Thiols C8H18S
2-Methyl-1-propanethiol Alkyl Thiols C4H10S
2-Methyl-2-propanethiol  Alkyl Thiols C4H10S
3-Methyl-1-butanethiol  Alkyl Thiols C5H12S
Butyl 3-mercaptopropionate  Alkyl Thiols C7H14O2S
Methyl 3-mercaptopropionate  Alkyl Thiols C4H8O2S
tert-Dodecylmercaptan mixture of isomers Alkyl Thiols C12H26S
tert-Nonyl mercaptan, mixture of isomers  Alkyl Thiols C9H20S
(11-Mercaptoundecyl)-N,N,N-trimethylammonium bromide  Functional Thiols C14H32BrNS
1-Mercapto-2-propanol  Functional Thiols C3H8OS
11-(1H-pyrrol-1-yl)undecane-1-thiol  Functional Thiols C15H27NS
11-(Ferrocenyl)undecanethiol  Functional Thiols C21H32FeS
11-Azido-1-undecanethiol Functional Thiols C11H23SN3
11-Mercapto-1-undecanol Functional Thiols C11H24OS
11-Mercapto-1-undecanol  Functional Thiols C11H24OS
11-Mercaptoundecanoic acid Functional Thiols C11H22O2S
11-Mercaptoundecanoic acid  Functional Thiols C11H22O2S
11-Mercaptoundecylhydroquinone  Functional Thiols C17H28O2S
12-Mercaptododecanoic acid  Functional Thiols C12H24O2S
12-Mercaptododecanoic acid  Functional Thiols C12H24O2S
12-Mercaptododecanoic acid NHS ester  Functional Thiols C16H27NO4S
16-Mercaptohexadecanoic acid  Functional Thiols C16H32O2S
16-Mercaptohexadecanoic acid  Functional Thiols C16H32O2S
3-Amino-1-propanethiol hydrochloride  Functional Thiols C3H9NS · HCl
3-Chloro-1-propanethiol Functional Thiols C3H7ClS
3-Mercapto-1-propanol  Functional Thiols C3H8OS
3-Mercaptopropionic acid Functional Thiols C3H6O2S
4-Mercapto-1-butanol  Functional Thiols C4H10OS
6-(Ferrocenyl)hexanethiol Functional Thiols C16H22FeS
6-Amino-1-hexanethiol hydrochloride Functional Thiols C6H15NS · HCl
6-Mercapto-1-hexanol  Functional Thiols C6H14OS
6-Mercaptohexanoic acid  Functional Thiols C6H12O2S
8-Mercapto-1-octanol  Functional Thiols C8H18OS
8-Mercaptooctanoic acid  Functional Thiols C8H16O2S
9-Mercapto-1-nonanol  Functional Thiols C9H20OS
[11-(Methylcarbonylthio)undecyl]hexa(ethylene glycol) methyl ether  Protected Thiols C26H52O8S
[11-(Methylcarbonylthio)undecyl]tetra(ethylene glycol)  Protected Thiols C21H42O6S
[11-(Methylcarbonylthio)undecyl]tri(ethylene glycol) acetic acid  Protected Thiols C21H40O7S
[11-(Methylcarbonylthio)undecyl]tri(ethylene glycol) methyl ether  Protected Thiols C20H40O5S
Hexa(ethylene glycol)mono-11-(acetylthio)undecyl ether  Protected Thiols C25H50O8S
S-(10-Undecenyl) thioacetate  Protected Thiols C13H24OS
S-(11-Bromoundecyl) thioacetate  Protected Thiols C13H25BrOS
S-(4-Cyanobutyl)thioacetate  Protected Thiols C7H11NOS
1,1′,4′,1′′-Terphenyl-4-thiol  Ring Thiols C18H14S
1,4-Benzenedimethanethiol Ring Thiols C8H10S2
1-Adamantanethiol  Ring Thiols C10H16S
1-Adamantanethiol Ring Thiols C10H16S
1-Naphthalenethiol Ring Thiols C10H8S
2-Phenylethanethiol Ring Thiols C8H10S
4,4′-Bis(mercaptomethyl)biphenyl  Ring Thiols C14H14S2
4-Mercaptobenzoic acid Ring Thiols C7H6O2S
9-Mercaptofluorene Ring Thiols C13H10S
Biphenyl-4,4′-dithiol  Ring Thiols C12H10S2
Cyclohexanethiol Ring Thiols C6H12S
Cyclopentanethiol Ring Thiols C5H10S
m-Carborane-1-thiol  Ring Thiols C2H12B10S
p-Terphenyl-4,4′′-dithiol Ring Thiols C18H14S2
Thiophenol  Ring Thiols C6H6S

 

 

Loading Range (nm2)
Charge (mV)
Smaller particles Larger particles Smaller particles Larger particles
SAMs
5
4
-27
-12

Composition

These nanoparticles are shipped in 18MEG DI water (default solution) and a number of other solvents. Not all gold nanoparticle/SAM combinations are soluble in all solvents. Please contact us if you have any questions.

Custom Formulation

Please contact us.

Quantity

This product is available in 0.25mL volumes and larger.

Introductory Kits

Please contact us.

Delivery

Standard sizes are in stock. Special order sizes are shipped in two weeks or less. All domestic shipments are sent Fed Ex Standard Overnight delivery, international Fed Ex Priority 2 day. No shipments on Fridays except for dried particles. Saturday shipping available for extra charge.

Functionalization

This product comes with a number of different covalent options.

Shelf Life/Storage Temperature

This product is guaranteed for six months and should be stored at 4 °C after opening. Care must be taken to only use sterile glassware when working with this product.

Toxicity

The product toxicity is based on the solvent chosen.

Certifications

Every order comes with a Certification of Analysis that includes the following information. We use calibration traceable:

UV-VIS (Agilent 8453) for extinction and concentration measurements

NIR (Cary 500) for NIR extinction and concentration measurements

DLS (Malvern Nano ZS) for zeta potential measurement

ICP-MS (Varian 820-MS) for gold mass measurements

TEM (Phillips CM-100 100KV) for sizing

Spherical Gold Nanoparticles UV VIS

How much thickness does the SAMs add?

Typically 0.2nm per carbon length.

How do I determine the concentration of the product?

Simply divide the number of nanoparticles (nps) found on the included COA by the amount of solution you add.

Why do you sell your rods as OD-mLs and what does this mean?

This is because unlike spherical gold nanoparticles, the conversion from OD to mg is not linear with nanorod diameter. Consequently, for the same OD, the weight of the nanorods increases with diameter. 50 OD-mLs means that if you resuspend the material in 1mL of solvent, you will have an absorption of OD50 through a 1mL optical path.

Do all nanoparticles with all SAMs work in all solvents?

No. There are many limitations. We request you contact us first if you are unsure.

What is the shelf life if I never open the package and keep refrigerated?

Many of these products need to be used right away. We offer a shelf life of 30 days.

Should I store in the refrigerator?

Yes.

How do you size your gold nanoparticles? Does the size include the capping agent?

We use three methods to specify our gold nanoparticles; TEM, UV VIS, and DLS. Each has its own advantages and disadvantages, and we use a weighted system to take advantage of each methods strengths. In the end, we place the strongest weight to the TEM method, particularly since we use samples sizes greater than 50 particles for each lot.

Do you really provide a TEM for my specific lot?

Yes, and not just for 5-10 particles, rather 50-100 are standard.

What is OD?

Optical Density (OD) is measured by UV-VIS. An Optical Density OD=1 corresponds to a transmission of 10% through a 1cm cuvette. Optical Density is a nice unit to use since Optical Densities correlate linearly to concentration. So an Optical Density of 1.2 is equal to 1.2 times the concentration of a gold nanoparticle solution that has an Optical Density of 1. We use OD and concentration interchangingly as it is easier to refer to a solution of OD=1 rather than 2.35e12 nanoparticles. For all spheres up to 200nm, OD=1 does refer to 0.05mg/mL.

What is PDI?

PDI refers to polydispersity index and is equal to the standard deviation of the particle sizes divided by the average size.

Will you provide me the loading for the reactive groups for my journal paper?

Yes

Will you provide me a Certificate of Analysis containing all the necessary information for my journal paper?

Yes.

Will you disclose details on how you manufacture the product?

Unfortunately no.

Can I choose any buffer?

That depends on the requested conjugation, but in general, yes. We will advise if we don't think that a particular buffer is optimal for a particular product.

Can you help me put together procedures to use the product?

Absolutely.

Can you perform these conjugations and still keep the nanorod SPR where I specify?

Yes.

Can you work with very short covalent ligands, like 4 carbon lengths and have the particles stable?

Yes!

"We were previously making our own gold nanoparticles using the commonly used technique of citrate reduction of Au(III). The colloids generated are broadly polydisperse, and we were concerned that our application of these particles in immuno-gold labeling of cells for optical coherence microscopy (OCM) would be utilizing only the large diameter tail of the distribution. We purchased the sampler package of NanoPartz gold spheres (30 nm, 50 nm, 70 nm, 90 nm) and examined each size carefully with dynamic light scattering, OCM, and spectrophotometry. Our measurements indicated diameters a couple nanometers larger than specifications (a result of measurements on the fully hydrated state?), and remarkable monodispersity - within specs. It is clear to us now that our early immuno-gold results were dominated by the largest diameter spheres of our early colloids. We are delighted by the NanoPartz monodisperse preparations and recommend them strongly!"

Dr. Richard C. Haskell 
Professor of Physics & Director of Physics Clinic 
Physics Department 
Harvey Mudd College



"The scientists at Nanopartz have developed a line of colloidal gold nanorods with extremely high monodispersity in size, shape, and mass. The surfactant layer is highly stable and readily displaced for biofunctionalization. In every test, in vitro and in vivo, these materials have exceeded our expectations."


Geoffrey A. von Maltzahn
NSF and Whitaker Graduate Fellow
Harvard-MIT Division of Health Sciences and Technology
Laboratory for Multiscale Regenerative Technologies

High colloidal stability of gold nanorods coated with a peptide-ethylene glycol: Analysis by cyanide-mediated etching and nanoparticle tracking analysis

P Free, G Conger, W Siji, JB Zhang… - Colloids and Surfaces B: …, 2016 - Elsevier
... Ethylene glycol-derived alkanethiol, HS-(CH 2 ) 11 -EG 6 , Mw 468, was purchased from Prochimia
(ProChimia Surfaces Sp. ... 25 nm diameter, 49 nm length) and 808 nm λ max wavelength (23 nm
diameter, 85 nm length) gold nanorods were purchased from Nanopartz Inc. ...

 

Biofunctionalized gold nanoparticles for SPR-biosensor-based detection of CEA in blood plasma

T Špringer, J Homola - Analytical and bioanalytical chemistry, 2012 - Springer
... AuNPs of 30 nm functionalized with a mixture of carboxy-terminated and hydroxy-terminated
thiols were obtained from Nanopartz, USA, at a ... Carboxy-terminated [HS–C 11 –(EG) 6 –OCH
2 –COOH] and hydroxy-terminated [HS–C 11 –(EG) 4 –OH] alkanethiols were purchased ...

 

Nanobiosensor for detection and quantification of DNA sequences in degraded mixed meats

ME Ali, U Hashim, S Mustafa, YB Man… - Journal of …, 2011 - dl.acm.org
... 35]. The oligo was labeled with an alkanethiol at one end and a fluorescent dye,
tetramethyl-rhodamine (TMR), at the other. ... al. [35] and Nanopartz's technical note
[36] and were found to be 2.01 × 1011 NPS/μL and 335 nM. ...

 

Enhancing sensitivity of surface plasmon resonance biosensors by functionalized gold nanoparticles: size matters

T Špringer, ML Ermini, B Špačková… - Analytical …, 2014 - ACS Publications
... terminated [HS–(CH 2 ) 11 –EG 6 –OCH 2 –COOH] and hydroxy-terminated [HS–C 11 –EG 4
–OH] alkanethiols were purchased ... Gold Nanoparticles Spherical AuNPs covalently functionalized
with neutravidin via a 2 nm polymer bridge were purchased from Nanopartz Inc., USA ...

 

Carbon nanotube bottles for incorporation, release and enhanced cytotoxic effect of cisplatin

J Li, SQ Yap, SL Yoong, TR Nayak, GW Chandra… - Carbon, 2012 - Elsevier
... It has been demonstrated that alkanethiols readily assemble as a monolayer on the surface of
gold [14], [15], [16], [17], [18], [19], [20], [21] and [22], which is facilitated by strong bonds between
gold and sulphur ... Spherical GNPs (4 nm diameter) were purchased from Nanopartz™. ...

 

[PDF] Immunoassay Test Strip for Microcystin-LR Detection

J Xu - 2010 - fau.digital.flvc.org
... Ab so rb a n ce wavelength Figure 3. Alkanethiols-AuNPs Figure 4. UV-Vis spectra of 20 nm and
5 nm colloidal gold The fluorescence spectra of colloidal were studied by Zhu and other ... 20 nm
colloidal gold (S01007B) was purchased from Nanopartz (Loveland, CO). 5 nm water ...

 

Multi‐Parametric Sensing Platforms Based on Nanoparticles

M Segev‐Bar, N Bachar, Y Wolf… - Advanced Materials …, 2017 - Wiley Online Library
... MCNPs thin films were made using 2 sets of nanoparticles: (a) a set of Au-NPs with fixed (Au)
core diamater but capped with a series of organic alkanethiols that have ... The baseline resistances
showed a clear dependency in the organic alkanethiol chain length and NP diameter ...

 

Single gold nanoparticle-based colorimetric detection of picomolar mercury ion with dark-field microscopy

X Liu, Z Wu, Q Zhang, W Zhao, C Zong… - Analytical chemistry, 2016 - ACS Publications
... Meanwhile, for oligopeptides, certain block units, such as Lys, have affinity for Hg 2+ . LODs
of this group vary between 26 nM and 20 μM. The third group includes alkanethiols and
derivatives of mercaptoaliphatic acid and urea with LODs of 0.5–100 nM. ...

 

The manufacturing method for these nanoparticles are based on our proprietary method. Many alkanethiols require special solvents and purification methods to optimize loading. Most of our synthesis require many days for correct functionalization, purification, and QA. With proper environments, SAM densities of over 5/nm2 can be achieved resulting in very stable gold nanoparticle products.

 

 

  Nanopartz™ Analytical Gold Nanoparticles
Stability (salt,pH,chemicals) Variable
Monovalent No
Nonspecific binding Yes
Sterilization Yes

 

 

  • High density conjugations and purifications
  • No sodium azide
  • No BSA
  • Well Characterized
  • Customer can select buffer
  • Customer can select gold nanoparticle type, size and/or SPR
  • Loading of all ligands is optimized

Example part number is B11-30-CYS-ETOH-50-0.25 where:

B11 - Product family number forAnalytical Gold Nanoparticles. For Gold Nanorods, its B12 and so forth.

30 - Sphere diameter in nanometers. Other choices are 1.8 to 1500

CYS - Covalent ligand, in this case Cysteamine.

ETOH - Solvent - in this case Ethanol. Other choices are Toluene and many others.

50 - Optical Density at 1mL, in this case OD=50, optional 250. For spheres this is 2.5mg.

0.25 - Volume (mL).

How to Order

Ordering by scrolling down and selecting the options from the selection below.

 

Home
» B- SAM Functionalized Gold Nanoparticles
Molecular Surface Modified Spherical Gold Nanoparticles
Molecular Surface Modified Spherical Gold Nanoparticles
Part Number: B11
Options: (DIAMETER)-(LIGAND)-(SOLVENT)-(OD-mLs)-(VOL)
Example Part Number: 30nm diameter spherical gold nanoparticle, Cysteamine coating, in Ethanol, 50 OD-mLS (2.5mg), in 0.25mL
B11-30-CYS-ETOH-50-0.25
 

UV-VIS

 NHS Ligand products are lyophilized
 DIH (18MEG DD DI Water)
ETOH (Ethanol)
ISO (Isopropanol)
ACE (Acetone)
DMSO (DMSO)
DMF (DMF)
ACT (Acetonitrile)
TOL (Toluene)
CHL (Chloroform)
SO (Silicon Oil)
HEX (Hexane)
HEP (Heptane)
DEC (Decanol)
DCM (DCM)
 50 OD-mLs = 2.5mg Au
250 OD-mLs = 12.5mg Au
Price$470.00
Molecular Surface Modified Gold Nanorods
Molecular Surface Modified Gold Nanorods
Part Number: B12
Options: (DIAM-SPR)-(LIGAND)-(SOLVENT)-(OD-mLs)-(VOL)
Example Part Number: 10nm diameter nanorod with a peak SPR = 850nm, Cysteamine coating, in Ethanol, 50 OD-mLS (2.5mg), in 0.25mL
B12-10-850-CYS-ETOH-50-0.25
 NHS Ligand products are lyophilized
 DIH (18MEG DD DI Water)
ETOH (Ethanol)
ISO (Isopropanol)
ACE (Acetone)
DMSO (DMSO)
DMF (DMF)
ACT (Acetonitrile)
TOL (Toluene)
CHL (Chloroform)
SO (Silicon Oil)
HEX (Hexane)
HEP (Heptane)
DEC (Decanol)
DCM (DCM)
 50 OD-mLs = 2.5mg Au for >=25nm diameter nanorods, 1.75mg for <25nm diameter nanorods
250 OD-mLs = 12.5mg Au and 8.75mg Au respectively
Price$470.00
Molecular Surface Modified Microgold
Molecular Surface Modified Microgold
Part Number: B13
Options: (DIAM/LENGTH)-(LIGAND)-(SOLVENT)-(WT)-(VOL)
Example Part Number: 75/500nm long microgold, Cysteamine coating, in Ethanol, 0.25mg, in 0.25mL
B13-75/500-CYS-ETOH-0.25-0.25
 NHS Ligand products are lyophilized
 DIH (18MEG DD DI Water)
ETOH (Ethanol)
ISO (Isopropanol)
ACE (Acetone)
DMSO (DMSO)
DMF (DMF)
ACT (Acetonitrile)
TOL (Toluene)
CHL (Chloroform)
SO (Silicon Oil)
HEX (Hexane)
HEP (Heptane)
DEC (Decanol)
DCM (DCM)
Price$470.00
Molecular Surface Modified Gold Nanowires
Molecular Surface Modified Gold Nanowires
Part Number: B14
Options: (DIAM-LENGTH)-(LIGAND)-(SOLVENT)-(WT)-(VOL)
Example Part Number: 75nm x 1000nm gold nanowire, cysteamine coating, in Ethanol, 0.25mg, in 0.25mL
B14-75/1000-CYS-ETOH-0.25-0.25
 NHS Ligand products are lyophilized
 DIH (18MEG DD DI Water)
ETOH (Ethanol)
ISO (Isopropanol)
ACE (Acetone)
DMSO (DMSO)
DMF (DMF)
ACT (Acetonitrile)
TOL (Toluene)
CHL (Chloroform)
SO (Silicon Oil)
HEX (Hexane)
HEP (Heptane)
DEC (Decanol)
DCM (DCM)
Price$470.00