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Spherical Gold Nanoparticles
Gold nanoparticles are one of the
most widely used classes of nanomaterials for chemical,
bioanalytical, biomedical, optical and nanotechnological
applications. While there are numerous methods known for the
synthesis of gold nanoparticles, the ability to control the size,
shape and monodispersity for gold nanoparticles is one of the
important areas in which few standard protocols have been
established to allow preparation of gold nanoparticles of desired
sizes, shapes and monodispersity in a systematic way. Such ability
is critical for many applications. We have developed a patent
pending technique which can form any desired size in the range of
5-100 nm diameters. The result is a gold nanoparticle that
when compared with citrate capped nanoparticles, have better size
and shape monodispersity, reduced batch to batch variation, and
improved reactivity.
Gold
Nanorods
The limitation on commercializing gold nanorods has always been
monodispersity and scaling. Up until now, nanorod production has
been limited to volumes of less than 100 ml. To overcome this
limitation, we have exclusively licensed rights to patent pending
nanorod manufacturing methods developed by Dr. Cathy Murphy at the
Univ. of South Carolina and Dr. Eugene Zubarev at Rice University.
This technology combined with our in-house proprietary methods
result in gram-scale synthesis of well-defined gold nanorods with a
near-quantitative yield. This means we can manufacture 5-10 liter
batches of nanorods that are highly monodisperse in size, shape, and
reactivity. Further, the production methods allow for tuning of the
nanorods to the desired absorbance peak.
Microgold
The first gold nanoparticle that can be seen in
white light microscopy. These nanoparticles are approximately
1 micron in size, and can be conjugated to carboxyl, amines,
neutravidin, and custom antibodies. Consequently, for in vitro
imaging this particle replaces the old technology of silver growth
enhancement of small gold nanoparticles. One step, tagging, no
enhancement is necessary.
Gold Nanowires
Trying to extend nanorod technology to work for
nanowires has been historically unsuccessful. We have recently
developed proprietary methods that will allow us to grow any length
nanowire, from 100 nm to 25 microns.
Pt and Pd coated Gold Nanorods
We combine the exceptional surface areas provided
by gold nanorods with the catalytic properties of Platinum and
Palladium coatings. These nanoparticles minimize the expense
and use of these precious materials while still offering all of the
catalytic advantages.
Polymer Conjugations
Probably the least
appreciated and most challenging part of our developments. As
opposed to traditional approaches to PEGylation, Nanopartz has
developed a proprietary method of generating a high-density
hydrophilic cage of polymers on gold nanoparticles,
providing an ultra-stable nanoparticle platform for in vitro, in
vivo, and many non-life science applications. Each family of
products, our in vivo nanorods, our in vitro spheres,
and our organic nanoparticles all have different formulations
optimized for that specific application.
For our organic
systems, we have developed an extremely innovative polymer scheme
that provides the longest lifetimes in the harshest solvent - and at
the highest temperatures - in the industry.
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