Nanopartz™ Custom Charged Gold Nanoparticles

Nanopartz™ Custom Conjugated Gold Nanoparticles includes the full line of monodisperse spherical, rod, microgold, and nanowire product familes for conjugation to customer specified charge requirements: negative, neutral, and positive. Not only is every batch completely purified, it is characterized including size, charge, monodispersity, aggregation, residual chemicals, and concentration. A Certificate of Analysis (COA) is provided for every order exhibiting TEM and UV-VIS images and data, as well as DLS data. Customers have a choice of radiation sterilization and endotoxin postprocessing.

Spherical Gold Nanoparticles (left to right) 0.9nm, 1.2nm, 1.8nm, 3nm, and 5nm

Custom Charged Spherical Gold Nanoparticles (2.5mg in 1mL)

Part #	Diam (nm)	NPS/mL
CC11-1.8	1.8	4.4E+16
CC11-2.2	2.2	2.4E+16
CC11-3	3	9.6E+15
CC11-4	4	4.1E+15
CC11-5	5	2.1E+15
CC11-10	10	2.7E+14
CC11-15	15	8.0E+13
CC11-20	20	3.4E+13
CC11-25	25	1.8E+13
CC11-30	30	1.0E+13
CC11-35	35	6.5E+12
CC11-40	40	4.3E+12
CC11-45	45	3.1E+12
CC11-50	50	2.2E+12
CC11-55	55	1.7E+12
CC11-60	60	1.3E+12
CC11-65	65	1.0E+12
CC11-70	70	8.2E+11
CC11-75	75	6.7E+11
CC11-80	80	5.5E+11
CC11-85	85	4.6E+11
CC11-90	90	3.9E+11
CC11-95	95	3.3E+11
CC11-100	100	2.9E+11
CC11-125	125	1.5E+11

Custom Charged Gold Nanorodz™ (OD 50 in 1mL)

Part #	Diam (nm)	Long Size (nm)	Peak SPR Wave (nm)	NPS/mL	Wt. conc (mg) (10-3)	A/R
CC12-10-1064	10	67	1064	1.81E+13	1750	6.7
CC12-10-980	10	59	980	2.09E+13	1750	5.9
CC12-10-900	10	50	900	2.47E+13	1750	5.0
CC12-10-850	10	45	850	2.78E+13	1750	4.5
CC12-10-808	10	41	808	3.10E+13	1750	4.1
CC12-10-780	10	38	780	3.36E+13	1750	3.8
CC12-10-750	10	35	750	3.70E+13	1750	3.5
CC12-10-700	10	29	700	4.44E+13	1750	2.9
CC12-25-980	25	146	980	1.91E+12	2500	5.9
CC12-25-850	25	113	850	2.54E+12	2500	4.5
CC12-25-808	25	102	808	2.83E+12	2500	4.1
CC12-25-780	25	94	780	3.08E+12	2500	3.8
CC12-25-750	25	86	750	3.38E+12	2500	3.5
CC12-25-700	25	73	700	4.06E+12	2500	2.9
CC12-25-650	25	60	650	5.07E+12	2500	2.4
CC12-25-600	25	47	600	6.77E+12	2500	1.9
CC12-25-550	25	34	550	1.01E+13	2500	1.4
CC12-40-750	40	138	750	8.26E+11	2500	3.5
CC12-40-700	40	118	700	9.91E+11	2500	2.9
CC12-40-650	40	97	650	1.24E+12	2500	2.4
CC12-40-600	40	76	600	1.65E+12	2500	1.9
CC12-40-550	40	55	550	2.48E+12	2500	1.4
CC12-50-700	50	147	700	5.07E+11	2500	2.9

Custom Charged Microgold

Part #	Diam (nm)	Length (nm)	NPS/ml	Wt. conc (mg/ml)	Molarity (pM)
CC13-500	75	500	5.87E+09	0.25	9.79E+00
CC13-1000	100	1000	1.65E+09	0.25	2.75E+00

Custom Charged Gold Nanowires

Part #	Diam(nm)	Length(nm)	mg/mL	AR	nps/mL
CC14-1000	75	1000	0.25	13	2.94E+06
CC14-2000	75	2000	0.25	27	1.47E+06
CC14-3000	75	3000	0.25	40	9.79E+05
CC14-4000	75	4000	0.25	53	7.34E+05
CC14-6000	75	6000	0.25	80	4.89E+05
CC14-7500	75	7500	0.25	100	3.92E+05
CC14-10000	75	10000	0.25	133	2.94E+05

Background

These particles utilize Nanopartz™ expertise as world leaders in gold conjugation and polymer coatings. Utilizing Nanopartz™ capabilities, customers now have the ability to have custom charges on gold nanoparticles. Customers detail the charge desired, and Nanopartz™ provide the resultant product completely characterized using NIST traceable TEM, UV VIS, DLS, HPLC, and ICP instrumentation. Most importantly, the customer will know the exact zeta potential of the nanoparticles and will be given options for sterilization and for endotoxin free products.

Features

Stable
Well Characterized
Customer can select gold nanoparticle type, size and/or SPR and charge

Benefits

Customer can focus on research and not on Nanopartz™ expertise
Quick turnaround

Nanopartz Custom Conjugated Gold Nanoparticles In Literature

[PDF] Antibody-conjugated Gold Nanoparticles integrated in a Fluorescence based Biochip

[PDF] from diva-portal.org

J Ljungblad - liu.diva-portal.org

... 3.1.1 Gold nanoparticles Citrate stabilized and PEG conjugated gold nanoparticles were bought
from Nanopartz, Salt Lake City, USA. The citrate stabilized nanoparticles arrived with a given
concentration of 4.08x109 particles/ml in water and a particle size of 110 nm. ...

Nanoparticles-New medical potential-Today and tomorrow

[PDF] from nanoarchive.org

T Chachibaia - Nano Studies, 2011 - nanoarchive.org

... It is unreasonable to generalize from just a few studies, because in recent years company
Nanopartz have announced about new manufacturing method, replacing undesirable
organic molecule of CTAB with polyethylene glycol (PEG). ...

[DOC] PASTGIN for diagnosing, monitoring, and treating breast cancer

[DOC] from duke.edu

Y Cheng, A Goktug, K Liu… - duke.edu

... Here, we propose to replace PEG coating in the original structure with carboxydextran coating
to create Carboxydextran-CONH-Herceptin structure around iron oxide which would make
“PASTGIN” more compatible for photoacoustic ... 20. “Photoacoustic Imaging.” Nanopartz.com. ...

22, 32, 52, 72-NS MSDS

FAQz

What is the exact charge on the particles?

That will be determined via DLS Zeta measurements and included on the COA. In general, the charges are -30, 0, and +30mV.

Can I choose any buffer?

That depends on the requested conjugation, but in general, yes. We will advise if we don't think that a particular buffer is optimal for a particular product.

Can you help me put together procedures to use the product?

Absolutely.

Can you perform these conjugations and still keep the nanorod SPR where I specify?

Yes.

Can you work with very short covalent ligands, like 4 carbon lengths and have the particles stable?

Yes!