Nanopartz^TM Gold Nanobeads^TM are manufactured using our proprietary and patent pending method that results in exact sizes, and highly monodisperse sizes and shapes, with the added advantage of a patent pending method that includes a covalent bonded  polymer cage  with carboxyl, methyl, biotin, or neutravidin terminal groups.  This formulation has been optimized for in vitro use and provides the following benefits:

• Stable from pH= 3 to 11

• Storage lifetime at room temperature up to one year (accelerated  testing has shown 70 C for 2 weeks)

• Stable in 1-2 M salt

• Can be suspended in most solvents

• May be concentrated to OD 5,000

• Charge control, +, -, or neutral

 

Composition

Gold colloid with a a formulation of polymer-caged nanoparticles with methyl, carboxyl, amine, biotin or neutravidin  functional groups, optimized for in vitro use. Excess active groups are reduced to less than 0.1% the concentration of the gold nanoparticles.

 

Diameter (nm)	Peak SPR Wavelength (nm)	NPS/ml	Wt. conc (mg/ml)	Wt. %	PPM	Molarity (pM)	Molar Ext. (M-1cm-1)	Absorption Molar Ext. (M-1cm-1)	Scattering Molar Ext. (M-1cm-1)	Size Dispersity %CV
5	514-520	2.1E+15	2322	0.23%	2322	3492600	2.86E+05	2.86E+05	0.00E+00	<20%
10	514-520	2.7E+14	2369	0.24%	2369	445440	2.24E+06	2.24E+06	0.00E+00	<20%
20	514-520	3.4E+13	2417	0.24%	2417	56811	1.76E+07	1.76E+07	0.00E+00	<10%
30	523	1.0E+13	2446	0.24%	2446	17032	5.87E+07	5.87E+07	0.00E+00	<6%
40	527	4.3E+12	2466	0.25%	2466	7246	1.38E+08	1.38E+08	4.00E+05	<4%
50	531	2.2E+12	2482	0.25%	2482	3734	2.68E+08	2.57E+08	1.04E+07	<4%
60	536	1.3E+12	2496	0.25%	2496	2172	4.60E+08	4.17E+08	4.37E+07	<4%
70	542	8.2E+11	2507	0.25%	2507	1374	7.28E+08	6.03E+08	1.24E+08	<4%
80	549	5.5E+11	2517	0.25%	2517	924	1.08E+09	7.93E+08	2.89E+08	<4%
90	558	3.9E+11	2525	0.25%	2525	651	1.54E+09	9.48E+08	5.88E+08	<4%
100	569	2.9E+11	2533	0.25%	2533	476	2.10E+09	1.01E+09	1.09E+09	<4%

 

 

Custom Formulation and Production

 

Quantity

• Volumes of 1 mL and 5 mL, OD 50 (concentration is 50x our bare gold nanoparticles) which amounts to 50 and 250 OD-mL.

• For larger quantities, or for orders amounting over 50 mL per annum, please contact sales for quantity pricing.

Delivery

• Shipped sealed in low retention micro-centrifuge containers.

• Specially formulated polymer cage.

• All are stored in PBS buffer at pH=7.4.

• Orders come with exact size and concentration calculation, along with a Certificate of Analysis for pH, volume, and optical density.

• Most conjugations ship in less than 1-2 weeks.

• All shipments are made Fed Ex Standard Overnight delivery. No shipments on Fridays.

Part #s

 

      PN# 60-T-P(A,B,C,M,N)-SSS-OD

• -T is type (R,S), rods (R) or spheres (S)

• -P(A,B,C,M,N) is conjugation; Methyl -PM; Carboxyl -PC; Amine -PA; Biotin -PB; Neutravidin -PN

• -SSS is nanoparticle size (nm) for spheres (5, 10, 20, 30, ...100); or peak SPR (nm) for rods (550, 600, 650, 700, 750)

• -OD is OD-mLs; 50 or 250 OD-mLs

• Spherical example: Spherical Nanobeads^TM, Carboxyl, 30 nm, 5 mL: 60-S-PC-30-250.

• Rod example: Rod Nanobeads^TM, Methyl, 780 nm, 1 mL: 60-R-PM-780-50

Price

• Amine, Biotin, Carboxyl, and Methyl: 50 OD-mL $480; 250 OD-mL $1920

• Neutravidin: 50 OD-mL $520; 250 OD-mL $2080

• Each product comes highly concentrated, 50 times greater than our regular bare gold nanoparticles.  We do this for a number of reasons detailed in our FAQz.  Further, our yield is about 50% so it takes over 100 mL of gold nanoparticles to make 1 mL of concentrated conjugated particles.