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Ntracker

NanopartzTM has developed a revolutionary new in vivo product - NtrackerTM nanorods specifically for use in biological, preclinical, and in vivo applications. NtrackerTM nanorods are coated in a proprietary dense layer of hydrophilic polymers that shield the gold surface and give the particles ultra-long circulation times in vivo. As opposed to other commercially available nanoparticles with short circulation times - such as quantum dots, NtrackerTM nanorods can be not only be used for imaging, but also for photothermal applications.  They have been rigorously tested in vivo to yield superior circulation times in a variety of mammalian species promoting great permeation into solid tumor cancers. NtrackerTM nanorods are available with transverse plasmon resonance peaks in the visible and near-infrared.

Composition

The gold nanorods are shipped in PBS at pH 7.4.

Custom Formulation and Production

10 nm axial sized nanorods are used for wavelengths 700 nm, 750 nm, 780 nm, 808 nm, and 850 nm since the 10 nm size offers the highest photothermal conversion per gram.  Refer to application and technical notes.

Quantity

This product is available in highly concentrated (OD 50) in 1 ml and 5 ml sizes which amounts to 50 and 250 OD-mLs.  For a 20g mouse, 0.150 ml per injection is required. 

Delivery

All orders come with a Certificate of Analysis for quality assurance.  Standard sizes are in stock.  Special order sizes will be shipped in two weeks or less.  All shipments are sent Fed Ex Standard Overnight delivery.  No shipments on Fridays. 

Conjugation

There are no conjugation possibilities with the NtrackerTM nanorods.  Consequently, it is strongly recommended that for conjugating the customer should purchase our NtherapyTM or NsenseTM nanorods prepared with amine- and carboxyl- terminations for the specific purpose of conjugating target antibodies.

 

Specification Overview

 

In batch size variation < 10% CV 
Shape monodispersity >95% nanorods
Surface charge (zeta) +40 mV typ
Axial sizes available 10 or 25 nm
Wavelength coverage 550-850 nm
pH 3-5
CTAB <0.1%

 

Part #  Transverse Diameter (nm) Longitudinal Size (nm) Peak LSPR Wave (nm) OD LSPR (AU) Peak TSPR Wave (nm) OD TSPR (AU) NPS/ml Wt. conc (mg/ml) Wt. % PPM Molarity (pM)
30-PM-850 10 45 850 50.0 512 12.50 2.6E+13 1785.7 0.1786% 1786 43699
30-PM-808 10 41 808 50.0 512 12.50 2.9E+13 1805.6 0.1806% 1806 48943
30-PM-780 10 38 780 50.0 512 12.50 3.1E+13 1745.8 0.1746% 1746 50982
30-PM-750 10 35 750 50.0 512 12.50 3.2E+13 1670.7 0.1671% 1671 53199
30-PM-700 10 29 700 50.0 512 12.50 3.3E+13 1483.6 0.1484% 1484 55617
                     
LSPR = Longitudinal SPR peak                  
TSPR = Transverse SPR peak                  
Shape monodispersity (% rods) > 95%                
Size variation +/-10% (both dimensions)              
Aspect ratio variation = Peak LSPR accuracy/96            
All specs typical.  May vary batch to batch.  Exact values are measured for each batch  

 

 

Product and Price List

 

To begin online shopping push on

30-PM-700-50 Ntracker In-Vivo GNRs  10 nm, SPR=700 nm, Methyl-Polymer, 50 OD-mL $480
30-PM-700-250 Ntracker In-Vivo GNRs  10 nm, SPR=700 nm, Methyl-Polymer, 250 OD-mL $1,920
30-PM-750-50 Ntracker In-Vivo GNRs  10 nm, SPR=750 nm, Methyl-Polymer, 50 OD-mL $480
30-PM-750-250 Ntracker In-Vivo GNRs  10 nm, SPR=750 nm, Methyl-Polymer, 250 OD-mL $1,920
30-PM-780-50 Ntracker In-Vivo GNRs  10 nm, SPR=780 nm, Methyl-Polymer, 50 OD-mL $480
30-PM-780-250 Ntracker In-Vivo GNRs  10 nm, SPR=780 nm, Methyl-Polymer, 250 OD-mL $1,920
30-PM-808-50 Ntracker In-Vivo GNRs  10 nm, SPR=808 nm, Methyl-Polymer, 50 OD-mL $480
30-PM-808-250 Ntracker In-Vivo GNRs  10 nm, SPR=808 nm, Methyl-Polymer, 250 OD-mL $1,920
30-PM-850-50 Ntracker In-Vivo GNRs  10 nm, SPR=850 nm, Methyl-Polymer, 50 OD-mL $480
30-PM-850-250 Ntracker In-Vivo GNRs  10 nm, SPR=850 nm, Methyl-Polymer, 250 OD-mL $1,920

 

 

Applications

 

In-Vivo

            Imaging

                     Photoacoustic Imaging

                              Optical Coherence Tomography

                              Two photon fluorescence 

            Therapeutics

                     Photothermal

                              Cancer

                              Viral

 

 
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NtrackerTM

 

NtrackerTM stability in Serum

 

NtrackerTM in Action

Adobe Acrobat®AN801 NTrackerTM for InVivo use

 

Technical Resources

 

Frequently Asked Questions (FAQz)


Adobe Acrobat®NtrackerTM Data Sheet

 

 

 Adobe Acrobat®NtrackerTM Product Profile

 

Storage and Shelf Life

 

Ordering Information

 

How do I order?

 

Related Technical Notes

 

Adobe Acrobat®Gold nanorods MSDS

 

Adobe Acrobat®Tech Note TN602 Nanopartz Gold Nanoparticles Handling and Storage

 

Adobe Acrobat®IN803 Gold nanorods as MPs for in vivo Imaging

 

Adobe Acrobat®TN802 Photothermal Characteristics of Gold Nanorods